a highly contagious virus disease causing fever, vomiting, and pus-filled sores on the skin that often leave pitted scars, or pockmarks. Smallpoxhas occurred in epidemics throughout history. A vaccination was developed and widely employed against this disease in the late eighteenth century. Through the use of vaccination the disease was becoming milder and rarer but cases were still being reported annually at the time of this lecture. —3rd South African published appr gls (14.4.92)